Showing posts with label antidepressant drugs. Show all posts
Showing posts with label antidepressant drugs. Show all posts

Monday, January 13, 2020

Elderly ‘Poisoned’ By Too Many Medications

Because little is known about the correct dosage for older patients and how different drugs react to each other, The Guardian reports the elderly are often “poisoned” with excess medication or combined drug reactions — called drug-drug reactions.
elderly
Drug dosage is tested in younger populations who do not have multiple diseases. Tests are not done on those over 60, according to the report, even though liver and kidney function declines as a person ages and senior citizens tend to have more adverse drug reactions than younger people.

More than half of American adults are regularly taking prescription medications and those numbers continue to climb. About a quarter of the population ages 65 to 69 are taking at least five prescription medications each day to treat chronic health conditions and that increases to nearly half of Americans ages 70 to 79. 

While every age group is at risk for being prescribed medications they do not need, the elderly are at particular risk. In addition, they are often prescribed narcotic painkillers, significantly increasing their chance of falling, which could lead to further disability or death.

One group of individuals who are at high risk of receiving prescription medications for diseases or illnesses they do not actually have are nursing home residents who suffer from dementia.

Adverse drug effects occur in at least 15% of seniors, and in nearly half of those cases the problem may have been prevented with greater communication between physicians and pharmacies treating the same patient.

Adding to the problem is the fact that there’s been a major rise in the number of antidepressants being prescribed for older adults over the last two decades, without proof that there is any increase in the number depressed.

Even though the number of depressed older adults living in care homes was unchanged, the use of antidepressants rose from 7.4% to 29.2%! Most of those prescribed antidepressants had not been diagnosed with depression.

Antidepressants are often ineffective for treating depression and pose risks to the elderly, including increasing the risk of falls, osteoporosis and fractures. Those types of injuries are usually treated with pain medication and that may lead to an entirely new problem.

An estimated 202,600 Americans died from opioid overdoses between 2002 and 2015 and 74% of farmers report being addicted to opioids, or know someone who is. Opioids are commonly prescribed for pain.

The massive increase in opioid sales and subsequent addiction rates came about after a premeditated marketing plan misinformed doctors about the drug’s addictive potential.

The same company that manufactured the addictive pain killers also came up with the medication to treat the addiction, all the while increasing their profits while thousands died. More than 70,200 Americans of all ages died from drug overdoses in 2017, according to the National Institute on Drug Abuse. 

If you or a loved one are elderly, don’t hesitate to speak to your doctor about any changes to your lifestyle choices that may reduce your need for medication and improve your health. Reasearch alternative pain treatments that don't require medication and stick to a diet filled with organically grown, nongenetically modified whole foods. 

Full Article & Source: 
Elderly ‘Poisoned’ By Too Many Medications

Sunday, December 22, 2019

Elderly ‘Poisoned’ By Too Many Medications

Because little is known about the correct dosage for older patients and how different drugs react to each other, The Guardian reports the elderly are often “poisoned” with excess medication or combined drug reactions — called drug-drug reactions.
elderly
Drug dosage is tested in younger populations who do not have multiple diseases. Tests are not done on those over 60, according to the report, even though liver and kidney function declines as a person ages and senior citizens tend to have more adverse drug reactions than younger people.

More than half of American adults are regularly taking prescription medications and those numbers continue to climb. About a quarter of the population ages 65 to 69 are taking at least five prescription medications each day to treat chronic health conditions and that increases to nearly half of Americans ages 70 to 79. 

While every age group is at risk for being prescribed medications they do not need, the elderly are at particular risk. In addition, they are often prescribed narcotic painkillers, significantly increasing their chance of falling, which could lead to further disability or death.
One group of individuals who are at high risk of receiving prescription medications for diseases or illnesses they do not actually have are nursing home residents who suffer from dementia.

Adverse drug effects occur in at least 15% of seniors, and in nearly half of those cases the problem may have been prevented with greater communication between physicians and pharmacies treating the same patient.

Adding to the problem is the fact that there’s been a major rise in the number of antidepressants being prescribed for older adults over the last two decades, without proof that there is any increase in the number depressed.

Even though the number of depressed older adults living in care homes was unchanged, the use of antidepressants rose from 7.4% to 29.2%! Most of those prescribed antidepressants had not been diagnosed with depression.

Antidepressants are often ineffective for treating depression and pose risks to the elderly, including increasing the risk of falls, osteoporosis and fractures. Those types of injuries are usually treated with pain medication and that may lead to an entirely new problem.

An estimated 202,600 Americans died from opioid overdoses between 2002 and 2015 and 74% of farmers report being addicted to opioids, or know someone who is. Opioids are commonly prescribed for pain.

The massive increase in opioid sales and subsequent addiction rates came about after a premeditated marketing plan misinformed doctors about the drug’s addictive potential.
The same company that manufactured the addictive pain killers also came up with the medication to treat the addiction, all the while increasing their profits while thousands died. More than 70,200 Americans of all ages died from drug overdoses in 2017, according to the National Institute on Drug Abuse. 

If you or a loved one are elderly, don’t hesitate to speak to your doctor about any changes to your lifestyle choices that may reduce your need for medication and improve your health. Reasearch alternative pain treatments that don't require medication and stick to a diet filled with organically grown, nongenetically modified whole foods. 

Full Article & Source: 
Elderly ‘Poisoned’ By Too Many Medications

Wednesday, July 3, 2019

These commonly prescribed medications may increase your risk of dementia, study finds

A study out of the University of Nottingham in the United Kingdom found there is a link between dementia and certain classes of anticholinergic drugs.

The drugs — particularly antidepressants, bladder antimuscarinics, antipsychotics and antiepileptic drugs — resulted in nearly "50% increased odds of dementia," according to the observational study published Monday in the peer-reviewed JAMA Internal Medicine journal.

Anticholinergic drugs help contract and relax muscles, according to Mayo Clinic. They can also be used to treat ulcers and prevent nausea. This is done by blocking a neurotransmitter in the brain, acetylcholine, from entering the nervous system.

Doctors prescribe these kinds of drugs to treat a variety of conditions, including chronic obstructive pulmonary disease, bladder conditions, allergies, gastrointestinal disorders and symptoms of Parkinson's disease.

The risk is only associated with 1,095 daily doses within a 10-year period, which is equivalent to an older adult taking a strong anticholinergic medication daily for at least three years.

"The study is important because it strengthens a growing body of evidence showing that strong anticholinergic drugs have long term associations with dementia risk," said study author Carol Coupland, professor of medical statistics in primary care at the University of Nottingham.

"It also highlights which types of anticholinergic drugs have the strongest associations. This is important information for physicians to know when considering whether to prescribe these drugs," she told CNN. "This is an observational study so no firm conclusions can be drawn about whether these anticholinergic drugs cause dementia."

The study warns people against stopping any of the medications listed without consulting their doctors.

The researchers found no significant increases in dementia risk associated with antihistamines, skeletal muscle relaxants, gastrointestinal antispasmodics, antiarrhythmics, or antimuscarinic bronchodilators, but associations were found among other classes of anticholinergic drugs.

An estimated 47 million people worldwide were living with dementia in 2015, while in the United States around 5.7 million people have Alzheimer dementia, according to the study.

Anticholergenic drugs include, but are not limited to, Artane, Bentyl, Oxytrol, Neosol, Symax and Vesicare. A full list can be found at Mayo Clinic.

Full Article & Source:
These commonly prescribed medications may increase your risk of dementia, study finds

Friday, October 28, 2016

Antidepressant Use Linked to Dementia

The authors of a study published in Alzheimer Disease and Associated Disorders found that elderly individuals using antidepressants were at significantly higher risk for dementia when compared with both depressed and not depressed nonusers. The study, which is one of the few long-term studies focusing on associations between antidepressants and dementia, followed a large group of participants for up to 18 years.

Antidepressants, including selective serotonin re-uptake inhibitors (SSRI), are commonly prescribed drugs in the U.S. Despite studies that have suggested these could have neuroprotective effects and that they can improve cognitive function in patients with Alzheimer’s dementia, these results are not consistent. Studies conducted with different populations have also found conflicting results with some finding that older antidepressants were associated with a reduced rate of dementia and others have found antidepressant use associated with cognitive impairment. Further, as the authors, led by Dr. Chenkun Wang, point out, elderly individuals are often underrepresented in clinical trials, therefore little is known about this antidepressant use in this population, particularly those with unimpaired cognitive functioning.

Over a span of two years (i.e. 1991-1993) 3,688 patients from a private care practice were enrolled in the study and included in the analysis – all of whom were 60 years of age or older. The researchers used medical history information from inpatient, outpatient, and emergency room records. Among the data retrieved were diagnoses of depression and dementia. Data regarding their antidepressant medication prescription and dispersal was also retrieved from their electronic medical record. Patients were divided into 5 groups:
  • Prescribed only SSRIs
  • Prescribed only non-SSRIs anti-depressants
  • Prescribed mixed anti-depressants (non-SSRIs & SSRIs)
  • Participants diagnosed with depression but not prescribed antidepressants (nonusers with depression)
  • Participants diagnosed who were not diagnosed with depression nor received antidepressants (nonusers without depression)
Results revealed that participants who were on SSRIs or non-SSRI antidepressants had a higher risk of dementia than the individuals diagnosed with depression who were not prescribed antidepressants. In addition, those who were on either type of antidepressant were at a higher risk of dementia than nonusers without depression.

Despite the limitations of the study, which include prescribing bias (e.g. doctors prescribing SSRIs to adults with cognitive impairments) and lack of depression and dementia severity measures, this is not the only study to yield these associations. A recent article on Medscape reporting on SSRIs and sleep disruption found that these antidepressants could cause significant sleep problems in the elderly, which could contribute to neurodegeneration leading to dementia. The authors of the study, which was presented at the Institute of Psychiatric Services: The Mental Health Services 2016 Conference, warn against ignoring sleep issues and side-effects of SSRIs and reiterate the importance of psychotherapy and holistic alternatives for elderly populations.

Full Article & Source:
Antidepressant Use Linked to Dementia

Tuesday, January 26, 2016

14 Lies That Our Psychiatry Professors in Medical School Taught Us


Dr. Gary Kohls
Myth # 1:

“The FDA (US Food and Drug Administration) tests all new psychiatric drugs”

False. Actually the FDA only reviews studies that were designed, administered, secretly performed and paid for by the multinational profit-driven drug companies. The studies are frequently farmed out by the pharmaceutical companies by well-paid research firms, in whose interest it is to find positive results for their corporate employers. Unsurprisingly, such research policies virtually guarantee fraudulent results.
Myth # 2:

“FDA approval means that a psychotropic drug is effective long-term”

False. Actually, FDA approval doesn’t even mean that psychiatric drugs have been proven to be safe – either short-term or long-term! The notion that FDA approval means that a psych drug has been proven to be effective is also a false one, for most such drugs are never tested – prior to marketing – for longer than a few months (and most psych patients take their drugs for years). The pharmaceutical industry pays many psychiatric “researchers” – often academic psychiatrists (with east access to compliant, chronic, already drugged-up patients) who have financial or professional conflicts of interest – some of them even sitting on FDA advisory committees who attempt to “fast track” psych drugs through the approval process. For each new drug application, the FDA only receives 1 or 2 of the “best” studies (out of many) that purport to show short-term effectiveness. The negative studies are shelved and not revealed to the FDA. In the case of the SSRI drugs, animal lab studies typically lasted only hours, days or weeks and the human clinical studies only lasted, on average, 4- 6 weeks, far too short to draw any valid conclusions about long-term effectiveness or safety!

Hence the FDA, prescribing physicians and patient-victims should not have been “surprised” by the resulting epidemic of SSRI drug-induced adverse reactions that are silently plaguing the nation. Indeed, many SSRI trials have shown that those drugs are barely more effective than placebo (albeit statistically significant!) with unaffordable economic costs and serious health risks, some of which are life-threatening and known to be capable of causing brain damage.
Myth # 3:

 “FDA approval means that a psychotropic drug is safe long-term”

False. Actually, the SSRIs and the “anti-psychotic” drugs are usually tested in human trials for only a couple of months before being granted marketing approval by the FDA. And the drug companies are only required to report 1 or 2 studies (even if many other studies on the same drug showed negative, even disastrous,  results). Drug companies obviously prefer that the black box and fine print warnings associated with their drugs are ignored by both consumers and prescribers. One only has to note how small the print is on the commercials.

In our fast-paced shop-until-you-drop consumer society, we super-busy prescribing physicians and physician assistants have never been fully aware of the multitude of dangerous, potentially fatal adverse psych drug effects that include addiction, mania, psychosis, suicidality, worsening depression, worsening anxiety, insomnia, akathisia, brain damage, dementia, homicidality, violence, etc, etc.
But when was the last time anybody heard the FDA or Big Pharma apologize for the damage they did in the past? And when was the last time there were significant punishments (other than writs slaps and “chump change” multimillion dollar fines) or prison time for the CEOs of the guilty multibillion dollar drug companies?  (Continue Reading)

Full Article & Source:
14 Lies That Our Psychiatry Professors in Medical School Taught Us